| Gram negative bacilli, glucose
non-fermenters. |
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Acinetobacter qualifies for inclusion in a
couple of categories of gram negative bacilli. It's also listed here because it
doesn't ferment glucose. |
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Burkholderia pseudomallei, and
Burkholderia mallei finally have been given their own genus name. We can
thank someone named Walter Burkholder of Cornell University for that. In the
past their taxonomic status had been undecided.
Burkholderia mallei causes the disease called
glanders.Glanders mainly affects horses, but also in descending order of
incidence, donkeys, mules, goats, dogs, and cats can be infected. "Human
infection, although not seen in the United States since 1945, has occurred
rarely and sporadically among laboratory workers and those in direct and
prolonged contact with infected, domestic animals."
"Bloodstream infections: Glanders bloodstream infections are
usually fatal within 7 to 10 days. Chronic infections: The chronic form of
glanders involves multiple abscesses within the muscles of the arms and legs or
in the spleen or liver." "Localized infections: If there is a cut or scratch in
the skin, a localized infection with ulceration will develop within 1 to 5 days
at the site where the bacteria entered the body. Swollen lymph nodes may also
be apparent. Infections involving the mucous membranes in the eyes, nose, and
respiratory tract will cause increased mucus production from the affected
sites." http://www.cdc.gov/ncidod/dbmd/diseaseinfo/glanders_g.htm
When Burkholderia mallei is isolated and identified
from blood, sputum, urine, or skin lesions the diagnosis can be made. Currently
there are no serologic tests.
"Burkholderia mallei is usually sensitive to
tetracyclines, ciprofloxacin, streptomycin, novobiocin, gentamicin, imipenem,
ceftrazidime, and the sulfonamides. Resistance to chloramphenicol has been
reported." http://www.cdc.gov/ncidod/dbmd/diseaseinfo/glanders_g.htm
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Burkholderia pseudomallei
"Melioidosis, also called Whitmores disease, is an
infectious disease caused by the bacterium Burkholderia pseudomallei.
Melioidosis is clinically and pathologically similar to glanders disease, but
the ecology and epidemiology of melioidosis are different from glanders.
Melioidosis is predominately a disease of tropical climates, especially in
Southeast Asia where it is endemic. The bacteria causing melioidosis are found
in contaminated water and soil and are spread to humans and animals through
direct contact with the contaminated source. Glanders is contracted by humans
from infected domestic animals.""In the United States, confirmed cases range
from none to five each year and occur among travelers and immigrants."
http://www.cdc.gov/ncidod/dbmd/diseaseinfo/melioidosis_g.htm
"Melioidosis is endemic in Southeast Asia, with the greatest
concentration of cases reported in Vietnam, Cambodia, Laos, Thailand, Malaysia,
Myanmar (Burma), and northern Australia. Additionally, it is seen in the South
Pacific, Africa, India, and the Middle East. In many of these countries,
Burkholderia pseudomallei is so prevalent that it is a common
contaminate found on laboratory cultures. Moreover, it has been a common
pathogen isolated from troops of all nationalities that have served in areas
with endemic disease."
http://www.cdc.gov/ncidod/dbmd/diseaseinfo/melioidosis_g.htm |
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Agricultural Use of Burkholderia (Pseudomonas) cepacia: A
Threat to Human Health? "In the past 2 decades, Burkholderia cepacia has
emerged as a human pathogen causing numerous outbreaks, particularly among
cystic fibrosis (CF) patients. One highly transmissible strain has spread
across North America and Britain, and another between hospitalized CF and
non-CF patients...."http://www.cdc.gov/ncidod/eid/vol4no2/holmes.htm
Burkholderia, (Pseudomonas) cepacia at Summer Camps for
Persons with Cystic Fibrosis, " Pseudomonas cepacia (PC) is a
multidrug-resistant, gram-negative bacillus that causes chronic colonization
and infection of the respiratory tract of persons with cystic fibrosis (CF). PC
colonization is usually difficult to eradicate with antimicrobial therapy and,
in some patients, infection is associated with rapid decline in pulmonary
function, increased hospitalization, and earlier death "http://www.cdc.gov/mmwr/preview/mmwrhtml/00020832.htm |
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Flavobacterium meningosepticum
PHIL ID# 1605 Title: Blood agar plate culture of
Flavobacterium meningosepticum, closeup. Content Provider(s): CDC/Dr. W.A.
Clark.

PHIL ID# 1604 Title: Blood agar plate culture of
Flavobacterium meningosepticum. Content Provider(s): CDC/Dr. W.A. Clark.

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Pseudomonas aeruginosa is not as common as for
example, E. coli. When Pseudomonas aeruginosa is seen in the
laboratory, it puts out a shiny pigment which can also be made to glow in the
dark. And in an effort presumably to avoid going unnoticed, gives off a
pleasantly appealing fruity fragrance which has been called grapelike. It's
sort of like saying, "Hey, here I am again!" Unfortunately in spite of its
brazen fanfare the bacterium is not welome. It is a pathogen. It can be
invasive. It is resistant to antibiotics and notoriously difficult to get rid
of. Any one of these characteristics would make a bacterium unpopular. But this
organism has all of them.
PHIL ID# 233 Title: Scanning Electron Micrograph of
Pseudomonas aeruginosa Content Provider(s): CDC/ _

In contradistinction to the more common members of the
family Enterobacteriacae, which when they are flagellated, posess
peritrichous flagella, Pseudomonas aeruginosa has flagella which are
polar . This can be seen in the EM image as thin green whisps at the ends of
the rods.

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Xanthomonas maltophilia has an affinity for
maltose, as can be seen from its name.

Xanthomonas
maltphilia, normal resolution gram stain. Blood culture.

Xanthomonas
maltophilia, high magnification gram stain. Blood culture. |
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